Archive for August 12th, 2012

Face in the Mirror More Distorted in Schizophrenia


Face in the Mirror More Distorted in SchizophreniaIndividuals with schizophrenia experience more intense perceptual illusions while gazing into a mirror than do healthy people, according to a new study.

The new research also showed that patients with schizophrenia were more likely to believe the illusions they see in the mirror were real.

The research highlights the underlying ego dysfunction and body dysmorphic disorder found in schizophrenia.

According to the researchers, gazing at one’s own reflected face under low light can lead to ghostly experiences called “strange-face in the mirror” illusions. No study has previously focused on mirror gazing in schizophrenic patients, who already experience delirium, hallucination and self mis-attribution.

Stefano Zago of the University of Milan conducted the study to compare strange-face apparitions in response to mirror gazing in 16 patients with schizophrenia and 21 mentally healthy controls.

Subjects took a 7-minute mirror-gazing test, after which they filled out a specially designed questionnaire asking them to describe their strange-face perceptions.

The results show a number of differences between patients with schizophrenia and mentally healthy controls.  Patients on average reported a greater total number of strange faces than controls, at 2.8 versus 1.5.

The types of strange faces also differed between patients and controls. Hugely deformed features were seen by all schizophrenia patients and 71% of controls, archetypal faces by 50% of patients and 19% of controls, and monstrous faces by 88% of patients and 29% of controls. Patients’ archetypical and monster faces were typically described as satanic beings.

Furthermore, patients tended to report greater intensity in the strange faces and were more likely to say that they felt real than controls.

Of note, mentally healthy participants felt dissociative experiences during the strange-face illusions and never identified with them.

Overall, the research suggests that strange-face illusions in schizophrenia can be caused by ego dysfunction, body dysmorphic disorder, or by misattribution of self-agency, said Zago.

The research is published in Schizophrenia Research.

Source:  Schizophrenia Research

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Can Thinking You Are Fat Make You Fat?


Can Thinking You Are Fat Make You Fat?  Researchers have found that normal-weight teens who think they are fat are more likely to grow up to be fat.

“Perceiving themselves as fat even though they are not may actually cause normal-weight children to become overweight as adults,” said Koenraad Cuypers, a researcher at the Norwegian University of Science and Technology.

Cuypers and his colleagues at the Department of Public Health and General Practice in NTNU’s Faculty of Medicine examined the obesity problem from a new angle: Their research looked at the relationship between perceived weights and actual weights in a study of teenagers and young adults.

The researchers note there are many reasons why teens who think they are fat — even when they are not — become overweight as adults.

One explanation may be related to psychosocial stress, which can be associated with gaining weight around the waist, the researchers said.

“Another explanation may be that young people who see themselves as fat often change their eating habits by skipping meals, for example. Research has shown that dropping breakfast can lead to obesity,” Cuypers said, adding that following a diet that you cannot maintain over time also is counterproductive, since the body strives to maintain the weight you had before you started the diet.

The researchers used data from the health survey Young-HUNT1, which was conducted from 1995-1997 and included 1,196 normal-weight teenagers of both sexes. Participants were later followed up in the Young-HUNT3 study, from 2006-2008, when they were between 24 and 30 years old.

Half of the participants still had normal weights as adults. But among those who were overweight, the researchers found that 59 percent of the girls who had felt fat as a teen became overweight in adulthood, as measured using body mass index or BMI. If waist circumference was used as the measure of obesity, then the percentage of teens who initially perceived themselves as fat and later became overweight as adults was 78 percent.

In contrast, 31 percent of the girls who did not consider themselves fat during adolescence were found in the follow-upstudy to be overweight as measured using BMI. That number was 55 percent as measured by waist circumference.

Normal-weight teens who rated themselves as fat in the initial HUNT study had a BMI in the followup study that was on average 0.88 higher than those who did not. They were also on average 3.46 centimeters larger as measured around the waist.

The study also shows that normal-weight girls were more likely than boys to rate themselves as overweight: 22 percent of girls and 9 percent of the boys saw themselves as fat in the first HUNT survey.

One explanation for this gender difference may be that the media’s focus on looks increasingly targets girls rather than boys, the researchers claim.

“Girls thus experience more psychosocial stress to achieve the ideal body,” Cuypers said. “Society needs to move away from a focus on weight, and instead needs to emphasize healthy eating habits, such as eating regular and varied meals and eating breakfast. Good sleep habits are also an advantage. And by reducing the amount that teens are transported to and from school and recreational activities, teens might also be able to avoid getting a ‘commuter belly.’”

Cuypers said he believes that the relationship between a perception of being overweight and the development of overweight is something that school systems and society as a whole must address to reverse the trend and reduce problems associated with obesity.

“The weight norms for society must be changed so that young people have a more realistic view of what is normal,” he said. “In school you should talk to kids about what are normal body shapes, and show that all bodies are beautiful as they are. And, last but not least, the media must cease to emphasize the supermodel body as the perfect ideal, because it is not.”

Cuypers’ results were published in the Journal of Obesity.

Source: Norwegian University of Science and Technology

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Migraines Painful — But Don’t Lead to Dementia


Migraines Painful -- But Don't Lead to DementiaResearch from Brigham and Women’s Hospital has shown that migraines are not associated with cognitive decline.

While migraines affect about 20 percent of the female population, there are many unanswered questions surrounding this complex disease, according to the researchers.

Previous studies linked migraines to an increased risk of stroke and structural brain lesions, but until this new study it had been unclear whether migraines had other negative consequences, such as dementia or cognitive decline.

“Previous studies on migraines and cognitive decline were small and unable to identify a link between the two,” said Pamela Rist, a research fellow in the Division of Preventive Medicine at BWH, and lead author on this study. “Our study was large enough to draw the conclusion that migraines, while painful, are not strongly linked to cognitive decline.”

The research team analyzed data from the Women’s Health Study, which included nearly 40,000 women, 45 years and older.

They analyzed data from 6,349 women who provided information about migraine status at baseline and then participated in cognitive testing during followup.

Participants were classified into four groups: No history of migraine, migraine with aura (transient neurology symptoms mostly of the visual field), migraine without aura, and past history of migraine. Cognitive testing was carried out in two-year intervals up to three times.

“Compared with women with no history of migraine, those who experienced migraine with or without aura did not have significantly different rates of cognitive decline,” she said.

“This is an important finding for both physicians and patients. Patients with migraine and their treating doctors should be reassured that migraine may not have long-term consequences on cognitive function.”

There is still a lot that is unknown about migraines, she acknowledged, noting that more research needs to be done to understand the consequences of migraine on the brain and to optimize treatment strategies.

The study was published online by the British Medical Journal.

Source: Brigham and Women’s Hospital

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